HealthMarch 19, 2025

Medi-Span Generic Product Identifier (GPI)

14-character hierarchy gives you power and flexibility that no static number can offer.

The Medi-Span® proprietary generic product identifier (GPI) is a unique concept with a long-proven track record. It stands out among data resources because it is capable of identifying drug products by a hierarchical therapeutic classification system.

The CEO of an HIT development company explains that the GPI structure helps his application identify more duplications and gaps in therapy:

You need to look at sub-groups, which is where Medi-Span, in my view, beats everyone else. It helps you find twice as many drug errors – errors that would lead to readmission – in half the amount of time.
CEO, HIT Development Company

How is the Medi-Span GPI used?

  • Can group identical, similar (same ingredient, different “sigs”), or unique drugs for medication reconciliation.
  • Impacts the specificity of clinical screening by taking into account contraindications specific to dosage form or route of administration.
  • Supports formulary development and maintenance.
  • Maps to NDCs, UPCs, and HRIs to support interoperability and information exchange.
  • Enables automated NDC inclusion/ exclusion without ongoing, routine maintenance.
  • Helps standardize drug lists to overcome problems created by different medication spellings and lexicons submitted from differing providers, pharmacies, and payers, simplifying comparisons

Why is the Medi-Span GPI unique?

Unlike other leading drug data solutions that assign drug products a static number, the GPI’s characters mean something.

  • 14-character value structure allows for the creation of complex drug lists with any level of granularity.
  • It ties to the Medi-Span proprietary generic product packaging code to help with purchasing decisions.
  • After decades of development, it is the standard within healthcare IT.
  • Ongoing surveillance of industry data allows us to regularly update GPIs to reflect the changing healthcare landscape.

So, what does this mean for you? Simply put, specificity and speed.

Pharmaceutical manufacturers

Pharmaceutical manufacturers use the GPI to collect and analyze real-world evidence of how a drug or drug class performs, review population health data, and better understand costs.

Retail pharmacy

Retail pharmacy uses all 14 characters of the GPI to enable pharmacists to find and process exact orders. For example, pharmacists can use the system to identify all brand and generic options for a medication prescribed as a 10 mg tablet.

PBMs and payers

PBMs and payers use the GPI to develop formularies and determine co-pay tiers. The GPI structure provides flexibility, allowing PBMs to include or exclude drugs from different tiers based on a variety of factors, including single ingredients.

Analytics firms and consultants

Analytics firms and consultants use the GPI to evaluate patient trends based on medication therapies; for example, all patients taking ACE inhibitors plus at least one other prescription drug.

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