Provide access to clinical and drug decision support where teams need it most — in the workflow

The electronic health record (EHR) system is an integral tool in care delivery, serving as the home base for patient data, care decisions, orders, documentation, and more. Integrating UpToDate®, UpToDate® Lexidrug™ (formerly Lexicomp®), and UpToDate Educate links into your EHR provides quick access to evidence-based clinical and drug decision support and patient-specific videos and digital content where you need it most, streamlining workflows, alleviating clinician efforts, and improving patient care.

Whether it’s through an embedded link or access to specific contextual content through an HL7 Infobutton, you can make the most of UpToDate solutions when they’re in your EHR.

Jump To Integrations

Benefits of integrating UpToDate solutions in the workflow

When you integrate UpToDate solutions into your EHR, you bring trusted clinical decision support even closer to the point of care, supporting improved outcomes and increased satisfaction. Key tasks can include:

Accessing over 12,400 clinical topics and 7,600 unique drug entries in 25 specialties
Accessing drug information content sets, databases, and decision models
Developing care recommendations or evaluating a lab result
Providing patient education aligned with clinical recommendations and medication plans
Accruing CME/CE/CPD credits through searches without extra logins 

Users said that having links to UpToDate in their EHR:

What our customers are saying

  • Providing quality care with EHR integrations 
  • Simple to set up and easy to use 
  • Capture continuing medical education credits while working

Both Lexidrug and UpToDate are integrated into our EMR informatics build, and they complement one another in providing reliable and comprehensive therapeutic clinical decision support (CDS) and drug-specific information. These [solutions] are core components of our systematic approach to providing effective pharmacotherapeutic care to our community. 
Mark Jordan, PharmD
Lexidrug linking was simple to set up, and the support was great. We had several direct contacts [at Wolters Kluwer] we could email or call, and the response was quick. Having links to Lexidrug integrated into our EHR system has made reaching valuable drug content easy. 
Amy Schuler
UpToDate Workflow Access in Cerner makes it easy for our providers. Before this new integration, they would use UpToDate as they were doing their job, but then they would have some extra logistics if they really wanted to capture their CMEs. With this method, they just access it in the context of their workflow… They’re loving it, and they’re getting their CMEs just by doing their jobs without having to do the extra log-in step. 
Brent Loftis

Workflow integrations with UpToDate and UpToDate Lexidrug (formerly Lexicomp)

Explore system integrations for UpToDate and UpToDate Lexidrug. Organizations using Epic, Oracle Cerner, and MEDITECH can integrate with both solutions.

  • Allscripts®

    Embedded search link
    Embedding UpToDate into Allscripts enables clinicians to get answers to their clinical questions within the clinical workflow. Allscripts Enterprise and Sunrise customers can set up links on the vertical toolbar on the left and the horizontal toolbar on the top. In Allscripts, the UpToDate link can be made accessible from every screen.

    AMA PRA Category 1 Credit™
    With single sign-on, clinicians log into Allscripts and can earn free AMA PRA Category 1 Credit™ or AANP contact hours when conducting an UpToDate search through Allscripts.

  • Cerner®

    Embedded search link
    The UpToDate free-text search link can be embedded into the Cerner Organizer top toolbar, making it easy to quickly search for a topic without opening a patient's chart.

    HL7 Infobutton

    • Tailored searches of UpToDate content relevant to a specific patient’s diagnosis, problems, medications, labs and other custom components
    • Support EHR's efforts to meet Promoting Interoperability requirements through linked clinical decision support.

    UpToDate HL7 Infobutton in the Patient Chart
    Clinicians highlight the relevant clinical term and select the HL7 Infobutton to automatically send that clinical term along with patient contextual information to UpToDate. The search results are displayed in an UpToDate results page, with continued access to all UpToDate content.

    AMA PRA Category 1 Credit™
    With an embedded link, clinicians may earn free AMA PRA Category 1 Credit™ or AANP contact hours with all searches.

    Physician satisfaction
    “We've integrated UpToDate into Cerner Millennium EMR across our entire network. This has been successful and delivers a seamless means of accessing clinical information just when it’s needed — during patient care. Our utilization is high because of the great content and our clinicians appreciate the CME program.”

    Neil Kudler, MD
    Medical Director, IT Services, Baystate Health, Springfield, MA

  • eClinicalWorks

    Embedded Search Box
    Accessing UpToDate through eClinicalWorks enables clinicians to get answers to their questions within the clinical workflow. Single sign-on enables eClinicalWorks clients to access UpToDate in one click. Just enter a search term in the UpToDate search box and access UpToDate search results. Just one click for easy return to the patient chart.

    AMA PRA Category 1 Credit™
    With the UpToDate link, clinicians may earn free AMA PRA Category 1 Credit™ or AANP contact hours when conducting an UpToDate search through eClinicalWorks.

    Quick implementation
    “I’d give our UpToDate integration into eClinicalWorks the highest rating possible. Implementation was as easy as flipping a switch and our physicians and interdisciplinary team love it.”

    Greg L. Wolverton, FHIMS
    Chief Information Officer, ARcare/Kentucky, Care Augusta, AR

  • Epic®

    UpToDate Free Text Links from Epic
    Users can perform a free-text search to UpToDate, making it easy to quickly search for any topic from the left and/or top health link tool bar.

    HL7 Infobutton

    • Tailored searches of UpToDate content relevant to a specific patient’s disease, condition, medication, lab results, age and gender
    • Support EHR's efforts to meet Promoting Interoperability requirements through linked clinical decision support

    With UpToDate interfaced with Epic via HL7 Infobutton, UpToDate content can be accessed from the following Epic EHR locations:

    • Problem List
    • Health Maintenance
    • Clinician Order Entry
    • Chief Complaint
    • Allergies Activity
    • Manage Orders Activity
    • Orders Navigator Section
    • Medications Activity
    • Results Review Activity
    • SmartSets, Order Sets, and Pathways
    • Vitals Navigator Section
    • Medications and Orders Navigator Section

    Integrated Patient Education
    Access to patient education is made simple. Easily integrate leading patient education content into your Epic workflow.

    AMA PRA Category 1 Credit™
    With the UpToDate CME link, clinicians may earn free AMA PRA Category 1 Credit™ or AANP contact hours.

    Physician satisfaction
    “Installation was very easy. It literally took a couple of hours for one person to get it all working.”

    David C. Kaelber, MD, PhD, MPH
    CMIO, MetroHealth Medical Center, Cleveland, OH

  • Intersystems TrakCare

    Search Options and Available Access Points
    Provides free-text search of UpToDate directly from a search box available in the TrakCare Patient Banner.

    Quick Search with Context – Using TrakCare InfoLink
    Provides free-text search for professional, patient, or graphics content from an UpToDate icon link in the TrakCare Patient Banner. Associated contextual patient information such as age may improve search results.

    Targeted Search – Using TrakCare InfoLink
    Provides relevant topics from a multilingual search term and patient contextual information. Access points include Diagnosis Entry - Diagnosis List - Diagnosis History, Problem List, Allergy List, Test Item Lists (Lab/Procedure), Order Lists, Medication List (Generic Name), and Generic Term List.

    Targeted Search – Using HL7 Infobutton
    Provides relevant topics from a coded medical term, English search terms and patient contextual information using International standards based HL7 Infobutton. Access points are identical to those use for above InfoLinks.

  • MEDITECH®

    HL7 Infobutton

    • Tailored searches of UpToDate content relevant to a specific patient’s diagnosis, lab results and medication
    • Support EHR's efforts to meet Meaningful Use / Promoting Interoperability requirements through linked clinical decision support

    HL7 Infobutton links to UpToDate from MEDITECH’s Patient Record
    A right click on the Infobutton located next to a term in the Problem List, Medication Panel, or Lab Panel screen will automatically send that clinical term and source information (problem, lab, medication) along with patient contextual information to UpToDate. The search results are displayed in an UpToDate results page, with continued access to all UpToDate content.

    Integrated Patient Education
    Access to patient education is made simple. Easily integrate leading patient education content into your MEDITECH workflow.

    AMA PRA Category 1 Credit™
    With an embedded link, clinicians may earn free AMA PRA Category 1 Credit™ or AANP contact hours with an HL7 Infobutton or Referential search.

    Physician satisfaction
    “UpToDate integration in MEDITECH is an absolute time saver. It’s so easy to use. You just right click and you’re there. It’s the easiest electronic initiative out there.”

    Stacey Johnson, MD
    Hospitalist, Beaufort Memorial Hospital, Beaufort, SC

  • NextGen®

    Embedded Link
    Embedding a link to UpToDate into NextGen enables clinicians to get answers to their clinical questions within the clinical workflow. NextGen customers can set up a link to UpToDate in the left navigation bar in the NextGen Patient Chart.

    AMA PRA Category 1 Credit™
    With single sign-on, clinicians log into NextGen and may earn free AMA PRA Category 1 Credit™ or AANP contact hours when conducting an UpToDate search through NextGen’s Patient Record.

    Efficient, quality care
    “UpToDate integrated into NextGen is timesaving and improves the quality of care I provide. It makes access to the most up-to-date clinical information seamless and easy. I love it.”

    Felix F. Carpio, MD, MPH
    Medical Director, Clinical Informatics, AltaMed, Los Angeles, CA

UpToDate Lexidrug medication decision integrations

  • Epic®

    Lexidrug Embedded Search link
    Embedding search links to Lexidrug in Epic enables clinicians to easily access clinical content from within their daily workflow. Location: Epic Clinical References in toolbar.

    Lexidrug Medication Literature Linking (Drug Reference Links)
    Link to key Lexidrug clinical information about a medication. These integrated URL links can point to any Lexidrug referential drug information database (Lexi-Drugs® core drug database, pediatric drug information, customized formulary databases, etc.) and can appear in MAR, Order Entry, or both.

    Black Box Warning Linking
    Black Box Warnings are critical drug information warnings published by the FDA. They appear in Lexidrug as part of the Warnings section of drug monographs. When linking is enabled, providers can directly access Black Box Warnings in the Lexidrug monograph from both Order Entry and MAR.

    Active Guidelines/AGL HL7 Infobutton
    Active Guidelines (AGL) uses HL7 Infobutton links to connect users directly to drug reference information relevant to their patients, based on chart elements like medications and orders. Context-specific links appear in the Problem List, Health Maintenance, Order Entry, Medication, and Chief Complaint and additional screens. 

  • Cerner® 

    Cerner Millennium Toolbar Linking
    Embedding links to Cerner Millennium® provides clinicians easier and faster access to the extensive Lexidrug referential drug content sets and guidance within the clinical workflow. Through a simple link and a top toolbar button, clinicians can perform quick searches using Lexidrug autocomplete to find the answers they need within seconds. 

  • MEDITECH®

    Meditech Embedded Drug Data in Lexidrug — HL7 Infobutton Integration
    Meditech customers can use HL7 Infobutton technology to access drug and clinical reference information from Lexidrug, from within the workflow. This integration supports ONC requirements for medication decision support components of Promoting Interoperability/ Meaningful Use. This integration is available in Magic, Client/Server, 6.x, and Expanse platforms.

    Use Infobutton to link to referential content in Lexidrug
    Problem list, Ordering screen in Provider Order Management, Reconcile Meds routine in Ambulatory Order Management, Certain Allergy Management routines, and various places on the Enterprise Medical Record Client/Server (C/S), 6.x, and Expanse and in Clinical Review (MAGIC). These are context-specific links related to specific drugs that appear within the EHR system. 

UpToDate Educate integrations


A robust suite of patient education materials — including a rich video collection — can be integrated into your EMR, digital health solutions, and beyond with UpToDate Educate.

Learn About UpToDate Educate
Get started today 
If you’re interested in learning more integrating UpToDate solutions in your EHR or system, request a conversation with a representative. 

Partnering with other clinical resources to support your care team

Wolters Kluwer is a leading provider of information for professionals and students in medicine, nursing, allied health and pharmacy. Wolters Kluwer's complementary offerings seamlessly integrate with the clinical workflow to support improved patient care and clinician satisfaction.
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